Description

Background: Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

Host species/Isotype:Rabbit/IgG

Cross reaction: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep

Immunogen:KLH conjugated synthetic peptide derived from human SQSTM1/p62:51-150/440.

Storage instructions:Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Concentration:1mg/ml

Specification：100ul

Purity:affinity purified by Protein A

Clonality:Polyclonal

Molecular weight:48kDa

Tested applications:

WB=1:500-2000

ELISA=1:500-1000

IHC-P=1:400-800

IHC-F=1:400-800

IF=1:100-500