Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Rabbit Anti-Vitamin D Binding protein antibody
Volum : 0.1ml
Reactivity : Human
WB=1/5000 – 1/20000. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).
IHC-P=1/100 – 1/250. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
ICC/IF=1/100 – 1/250.
Anti-gen synonyms :Synthetic peptide within Human Vitamin D Binding protein aa 250-350. The exact sequence is proprietary.
Uniprot No. :P02774
Host : Rabbit.
Clonality : Polyclonal
Isotopes : IgG
Concentration : 1mg/1ml
Purification : affinity purified by Protein A
Storage : May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Research Area : Cellular Immunology Signal transduction