[:en]Vitamin K2 is a fat-soluble vitamin. It is one of the most important vitamins in the human body. It is usually synthesized by some biosynthesis techniques. Vitamin K2 is mostly found in fermented foods, and many people in daily life often lack this vitamin. Therefore, it is necessary to have a better understanding of its efficacy in order to attract people’s attention.
Vitamin K2 is the only biologically active form of vitamin K. It is used to accelerate blood clotting, maintain clotting time, and treat hemorrhagic disease caused by vitamin K deficiency. Its function on the human body is mainly reflected in the treatment and prevention of osteoporosis, so it has some health care functions as well as some medicinal functions.
Osteoporosis mainly shows symptoms: low back pain, leg cramps, lack of walking; shortened length, hunchback; fractures and respiratory disorders, often occur in middle-aged and elderly menopausal women. Vitamin K2 has a significantly more anti-osteoporosis effect than vitamin K1 and has its unique two-way regulation of anti-osteoporosis mechanisms.
A.promote bone mineralization: osteocalcin can promote calcium deposition, increase bone mineralization rate, maintain normal calcification and crystallization of bone and cartilage mineralization rate, directly reflecting bone formation and bone reconstruction.
B.Promote bone formation: Vitamin K2 is a bone-specific gene transcriptional regulator that induces the expression of osteoblast markers through steroids and heterogeneous receptors, enhances the accumulation of collagen, improves bone mass, and promotes bone formation.
C.inhibition of bone resorption: osteoclasts are ** cells capable of absorbing bone, and the acidic environment caused by proton pump causes osteocalcin dissolution and cathepsin to dissolve bone matrix.
2.anti-arterial calcification and osteoarthritis
Vitamin K2 has a strong inhibitory effect on cartilage and vascular calcification, and can effectively remove abnormal calcium spots, and its biological activity depends on the level of vitamin K2 in the body. Studies have shown that osteoporosis, osteoarthritis and arteriosclerosis have a common pathogenic factor – vitamin K2 deficiency.
Vitamin K2 ultimately leads to cell cycle arrest or cell death by negatively regulating tyrosine and phosphatase activities associated with cell carcinogenesis, as well as regulating regulatory factors associated with cell proliferation.
Vitamin K2 has stronger antioxidant activity than vitamin E and coenzyme Q10, and has remarkable skin beauty and anti-aging effects.
Vitamin K2 is mostly found in fermented foods such as natto, sauerkraut and some cheeses, but these foods are generally lacking in the daily diet of Chinese people. In order to maintain bone health and prevent osteoporosis, healthy adults need to add about 50-120 micrograms of vitamin K2 per day. The amount of vitamin K2 supplemented in osteoporosis and skeletal sub-health needs to increase.[:]