Description
English name | Mitofusin 2 |
Chinese name | 线粒体融合蛋白Mfn2抗体 |
Alias | CMT2A; CMT2A2; MARF; CPRP 1; CPRP1; Fzo; HSG; hyperplasia suppressor gene; Hypertension related protein 1; MFN 2; Mfn2; MFN2_HUMAN; Mitochondrial assembly regulatory factor; Mitofusin-2; Mitofusin2; Transmembrane GTPase MFN2. |
research field | 心血管 细胞生物 免疫学 神经生物学 |
Antibody source | Rabbit |
Clone type | Polyclonal |
cross reaction | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, |
Application | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
molecular | 83kDa |
Cell location | 细胞浆 细胞膜 |
form | Lyophilized or Liquid |
concentration | 1mg/ml |
Immunogen | KLH conjugated synthetic peptide derived from human Mitofusin 2:1-120/757 |
Subtype | IgG |
Purification | affinity purified by Protein A |
Storage liquid | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Preservation conditions | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Product introduction | background: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].Subunit: Forms homomultimers and heteromultimers with MFN1. Subcellular Location: Tissue Specificity: DISEASE: Similarity: SWISS: Gene ID: |