Description
English name | Thyroid peroxidase |
Chinese name | 甲状腺过氧化物酶抗体 |
Alias | MSA; PERT_HUMAN; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX. |
Size | USD 980/100UL |
100ul | |
research field | |
Antibody source | Rabbit |
Clone type | Polyclonal |
cross reaction | Human, Mouse, Rat, |
Application | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
molecular | 101kDa |
Cell location | 细胞膜 细胞外基质 Extracellular matrix of cell membrane |
form | Lyophilized or Liquid |
concentration | 1mg/ml |
Immunogen | KLH conjugated synthetic peptide derived from human Thyroid peroxidase:111-210/933 <Extracellular> |
Subtype | IgG |
Purification | affinity purified by Protein A |
Storage liquid | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Preservation conditions | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Manufacturer | GLORYBIOS |
PubMed | PubMed |
Product introduction | background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].Function: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). Subunit: Subcellular Location: Post-translational modifications: DISEASE: Similarity: SWISS: Gene ID: |